Hantavirus is a virus that is found in the urine, saliva, or droppings of infected deer mice and some other wild rodents (cotton rats, rice rats in the southeastern Unites States and the white-footed mouse). It causes a rare but serious lung disease called Hantavirus pulmonary syndrome (HPS). The virus does not remain active for long once outside of its host -- less than 1 week outdoors and a few hours when exposed to direct sunlight.
The virus was first reported in Canada in 1994 with 3 cases in British Columbia. Since then, about 50 cases have been reported, mostly in western Canada (Manitoba, Saskatchewan, Alberta and British Columbia).
People can contract the Hantavirus infection through inhalation of respirable droplets of saliva or urine, or through the dust of feces from infected wild rodents, especially the deer mouse. Transmission can also occur when contaminated material gets into broken skin, or possibly, ingested in contaminated food or water. Person-to-person transmission in North America has not been reported. A few situations of Hantavirus pulmonary syndrome in South America suggests person-to-person transmission is possible. However, the viruses isolated in South America are genetically distinct from those described in North America.
The disease caused by Hantavirus is called Hantavirus pulmonary syndrome. Symptoms appear within 1 to 5 weeks after exposure. The average is 2 to 3.5 weeks. This disease is extremely serious since 50-60% of the people who get the disease die. The disease begins as a flu-like illness. In the early stage, a worker may experience fever, chills, muscle aches, headaches, nausea, vomiting, and shortness of breath, rapid heartbeat and gastrointestinal problems. However, the disease progresses rapidly and infected people experience an abnormal fall in blood pressure and their lungs will fill with fluid. Severe respiratory failure, resulting in death, can occur within a few days of the early stage symptoms.
There is no specific vaccine, treatment or cure for Hantavirus infection but early recognition and medical care in an intensive care unit can help with recovery. Infected people may be given medication for fever and pain and oxygen therapy.
Cases of Hantavirus infection contracted in Canada and the United States have been associated with these activities:
For workers that might be exposed to rodents as part of their normal job duties, employers are required to comply with relevant occupational health and safety regulations in their jurisdiction. Typically, employers are required to develop and implement an exposure control plan to eliminate or reduce the risk and hazard of Hantavirus in their workplace.
There are no vaccines against Hantavirus. Since human infection occurs through inhalation of contaminated material, clean-up procedures must be performed in a way that limits the amount of airborne dust. Treat all mice and droppings as being potentially infected. People involved in clean-up activities where there are not heavy accumulation of droppings should wear disposable protective clothing and gloves (neoprene, nitrile or latex-free), rubber boots and a disposable N95 respirator. For cleaning up rodent contaminated areas with heavy accumulations of droppings it is necessary to use powered air-purifying (PARP) or air-supplied respirators with P100 filters and eye or face protection to avoid contact with any aerosols.
Dead mice, nests and droppings should be soaked thoroughly with a 1:10 solution of sodium hypochlorite (household bleach). Bleach kills the virus and reduces the chance of further transmission. The contaminated material should be placed in a plastic bag and sealed for disposal. Disinfect by wet-wiping all reusable respirator surfaces, gloves, rubber boots and goggles with bleach solution. All disposable protective clothing, gloves and respirators should be placed in plastic bags and sealed for disposal. Please contact your local environmental authorities concerning approved disposal methods.
Thoroughly wash hands with soap and water after removing the gloves.
The U.S. Centers for Disease Control and the Workers' Compensation Board of British Columbia have guidelines that cover a variety of workplace situations. For more details on risk assessment and precautions for specific situations not clearly addressed by existing guidelines contact specific agencies responsible for such detailed information, for example, your local public health office.
Hantavirus. US Centers for Disease Control
Document last updated on October 20, 2008